By Shi-Jiang Lu, Qiang Feng, Jennifer Park, Loyda Vida, Bao-Shiang Lee, Michael Strausbauch, Peter Wettstein, George Honig, Robert Lanza

Human erythropoiesis is a complex multistep process that involves the differentiation of early erythroid progenitors to mature erythrocytes. Here we show that it is feasible to differentiate and mature human embryonic stem cells (hESCs) into functional […]

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Growing new body parts, reversing paralysis, stretching the limits of the human life span: This trailblazing stem cell researcher believes it is all within our reach.

Discover Magazine

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By: Sadhana Agarwal, Katherine L. Holton, Robert Lanza

Differentiation of human embryonic stem cells (hESCs) to specific functional cell types can be achieved using methods that mimic in vivo embryonic developmental programs. Current protocols for generating hepatocytes from hESCs are hampered by inefficient differentiation procedures that lead to low yields and large cellular heterogeneity. We […]

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Recent evidence suggests the existence of progenitor cells in adult tissues that are capable of differentiating into vascular structures as well as into all hematopoietic cell lineages. Here we describe an efficient and reproducible method for generating large numbers of these bipotential progenitors—known as hemangioblasts—from human embryonic stem (hES) cells using an in vitro differentiation system.

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Source: TheNewAmericanScholar.org

Vice-President of Research & Scientific Development, Robert Lanza, M.D.’s, provocative new theory that time and space do not exist as physical realities independent of humans (and animals) has been published in a feature article “A New Theory of the Universe” in the Spring issue of “The American Scholar”, one of the nation’s leading literary and intellectual publications.

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Bruce A Fenderson, Ph.D. (Thomas Jefferson University)

This beautiful hardcover book provides a concise and complete introduction to the theory and practice of stem cell research. It includes 69 definitive chapters on topics ranging from “molecular bases of pluripotency” and “nuclear cloning and epigenetic reprogramming” to “ethics of human stem cell research.” The primary focus is on cellular and developmental biology.

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By: Gosta Gahrton, The New England Journal of Medicine, June 29, 2006

After Ernest A. MCCulloch and James E. Till received the Albert Lasker Medical Research Award in Basic Research in 2005, they wrote a commentary in Nature Medicine. In it, they asked themselves, “Why now?” After all, their papers on the colony-assay model of cells from the mouse spleen—which described for the first time the hematopoietic stem cell of the bone marrow as a cell that is capable of both self-renewal and differentiation—are more than 40 years old. This book seems to have the answers.

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Steve Goldman (University of Rochester Medical Center)

The definition of a stem cell—like that of beauty—lies in the eyes of the beholder. Do stem cells strictly refer to embryonic stem cells and primordial germ cells—the pluripotent and self-renewing derivatives of blastocysts and embryonic gonads? Or should we include the multipotent but tissue-specified precursors of fetal organogenesis?

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Source: Scientific American June 2004 issue

Stem cells raise the prospect of regenerating failing body parts and curing diseases that have so far defied drug-based treatment. Patients are buoyed by reports of the cells’ near-miraculous properties, but many of the most publicized scientific studies have subsequently been refuted, and other data have been distorted in debates over the propriety of deriving some of these cells from human embryos.

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